Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ceruloplasmin gene variants are associated with hyperferritinemia and increased liver iron in patients with NAFLD.

Journal of hepatology - 1 Sept 2021

Corradini Elena, Buzzetti Elena, Dongiovanni Paola, Scarlini Stefania, Caleffi Angela, Pelusi Serena, Bernardis Isabella, Ventura Paolo, Rametta Raffaela, Tenedini Elena, Tagliafico Enrico, Fracanzani Anna Ludovica, Fargion Silvia, Pietrangelo Antonello, Valenti Luca Vittorio

Abstract excerpt

BACKGROUND & AIMS: Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disorder resulting from genetic and environmental factors. Hyperferritinemia has been associated with increased hepatic iron stores and worse outcomes in patients with NAFLD. The aim of this study was to evaluate the prevalence of variants of iron-related genes and their association with hyperferritinemia, hepatic iron stores and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Ceruloplasmin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Genetic Variation

Share to Iron Overload

Share to Non-alcoholic Fatty Liver Disease

Source

Identifiers

PMID: 33774058
DOI: 10.1016/j.jhep.2021.03.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ceruloplasmin gene variants are associated with hyperferritinemia and increased liver iron in patients with NAFLD.PMID 33774058Read ↗

Genetic factors that affect nonalcoholic fatty liver disease: A systematic clinical review.Semantic proximity Read ↗

Genetic Variations and Nonalcoholic Fatty Liver Disease: Field Synopsis, Systematic Meta-Analysis, and Epidemiological Evidence.Semantic proximity Read ↗

Alpha 1-antitrypsin mutations in NAFLD: high prevalence and association with altered iron metabolism but not with liver damage.Semantic proximity Read ↗

Ferroportin disease: a systematic meta-analysis of clinical and molecular findings.Semantic proximity Read ↗

The A736V TMPRSS6 polymorphism influences hepatic iron overload in nonalcoholic fatty liver disease.Semantic proximity Read ↗

Hyperferritinemia is a risk factor for steatosis in chronic liver disease.Semantic proximity Read ↗

Serum ferritin level is associated with liver fibrosis and incident liver-related outcomes independent of HFE genotype in the general population.Semantic proximity Read ↗

Iron status and non-alcoholic fatty liver disease: A Mendelian randomization study.Semantic proximity Read ↗

Associations between metabolic hyperferritinaemia, fibrosis-promoting alleles and clinical outcomes in steatotic liver disease.Semantic proximity Read ↗

Genetic variants in adult liver diseases.Semantic proximity Read ↗

DISTINCT PHENOTYPE OF NON-ALCOHOLIC FATTY LIVER DISEASE IN PATIENTS WITH LOW LEVELS OF FREE COPPER AND OF CERULOPLASMIN.Semantic proximity Read ↗

MRI-Based Iron Phenotyping and Patient Selection for Next-Generation Sequencing of Non-Homeostatic Iron Regulator Hemochromatosis Genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.