Article
DISTINCT PHENOTYPE OF NON-ALCOHOLIC FATTY LIVER DISEASE IN PATIENTS WITH LOW LEVELS OF FREE COPPER AND OF CERULOPLASMIN.
Arquivos de gastroenterologia - 1 Jan 2000
Nunes Vinicius S, Andrade Adriana R, Guedes Ana L V, Diniz Marcio A, Oliveira Claudia P, CanÇado Eduardo L R
Abstract excerpt
BACKGROUND: Copper deficiency has been linked to alterations in lipid metabolism and hepatic steatosis. Oxidative stress plays a role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). One of the enzymes that neutralize oxidative stress is Cu/Zn superoxide dismutase, which depends on the availability of adequate amounts of copper. OBJECTIVE: Correlate the levels of ceruloplasmin and of...
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