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Article

Genetic factors that affect nonalcoholic fatty liver disease: A systematic clinical review.

World journal of gastroenterology - 7 Aug 2016

Severson Tyler J, Besur Siddesh, Bonkovsky Herbert L

Abstract excerpt

AIM: To investigate roles of genetic polymorphisms in non-alcoholic fatty liver disease (NAFLD) onset, severity, and outcome through systematic literature review. METHODS: The authors conducted both systematic and specific searches of PubMed through December 2015 with special emphasis on more recent data (from 2012 onward) while still drawing from more historical data for background. We identified several...

Topics

Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Genetic Predisposition to Disease
Heme Oxygenase-1
Humans
Iron
Lipase
Membrane Proteins
Non-alcoholic Fatty Liver Disease
Polymorphism, Genetic
Sterol Esterase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27547017
DOI: 10.3748/wjg.v22.i29.6742
PMCID: PMC4970479

Genes

FTO
HFE
LIPA
PNPLA3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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