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MiR‐155 promotes colitis‐associated intestinal fibrosis by targeting HBP1/Wnt/β‐catenin signalling pathway

26 Mar 2021

Abstract excerpt

Intestinal fibrosis is the most common complication of Crohn's disease (CD) that is one major disorder of inflammatory bowel disease (IBD), but the precise mechanism remains unclear. MiR-155 has been involved in fibrotic diseases. Here, we determined the role of miR-155 in regulating intestinal fibrosis. MiR-155 levels were significantly up-regulated in CD patients with intestinal stricture CD. The overexpression...

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Share to Congenital gastrointestinal and neural anomalies
Share to MicroRNA in disease regulation
Share to Wnt/β-catenin signaling in development and cancer

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PMID: 33769664
DOI: 10.1111/jcmm.16445

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