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Article

Decreased expression of ARID1A invasively downregulates the expression of ribosomal proteins in hepatocellular carcinoma.

Biomarkers in medicine - 1 May 2021

Zhao Jing, Xu Weiran, Zhang Yu, Lv Xiaomin, Chen Yiran, Ju Gaoda, Yang Fang, Lin Li, Rao Xiaosong, Guo Ziwei, Xing Tao, Li Li, Liang Jun

Abstract excerpt

Background: There was increasing evidence showing that ARID1A alterations correlated with higher tumor mutational burden, but there were limited studies focusing on the adaptive mechanisms for tumor cells to survive under excessive genomic alterations. Materials & methods: To further explore the adaptive mechanisms under ARID1A alterations, we performed RNA sequencing in ARID1A knockdown hepatocellular carcinoma...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 33769075
DOI: 10.2217/bmm-2020-0464

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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