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Article

FOXD1 regulates cell division in clear cell renal cell carcinoma

24 Mar 2021

Abstract excerpt

Abstract Background Forkhead transcription factors control cell growth in multiple cancer types.Foxd1is essential for kidney development and mitochondrial metabolism, but its significance in renal cell carcinoma (ccRCC) has not been reported. Methods Transcriptome data from the TCGA database was used to correlateFOXD1expression with patient survival.FOXD1was knocked out in the 786-O cell line and known targets...

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PMID: 33761914
DOI: 10.1186/s12885-021-07957-8

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