Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of cell division cycle‑associated 5 promotes cell apoptosis by activating DNA damage response in clear cell renal cell carcinoma

31 May 2022

Abstract excerpt

Cell division cycle‑associated 5 (CDCA5) protein, which is involved in cohesion, contributes to cell cycle regulation and chromosome segregation by maintaining genomic stability. Accumulating evidence indicates that CDCA5 expression is upregulated in a number of types of cancer associated with a poor prognosis. However, the biological function of CDCA5 in clear cell renal cell carcinoma (ccRCC) remains largely...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Epigenetics and DNA Methylation
Share to Ferroptosis and cancer prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35642672
DOI: 10.3892/ijo.2022.5377

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of cell division cycle‑associated 5 promotes cell apoptosis by activating DNA damage response in clear cell renal cell carcinomaPMID 35642672Read ↗

Loss of CDCA5 Promotes Cell Apoptosis by Activating the DNA Damage Response in Clear Cell Renal Cell CarcinomaSemantic proximity Read ↗

CDCA5 is a potent therapeutic target of clear cell renal cell carcinomaSemantic proximity Read ↗

CDCA7: A Comprehensive Pan-Cancer Analysis Reveals its Prognostic Significance, Immune Correlations, and Therapeutic PotentialSemantic proximity Read ↗

High expression of CDCA7 predicts poor prognosis for clear cell renal cell carcinoma and explores its associations with immunitySemantic proximity Read ↗

Knockdown of MAPK14 inhibits the proliferation and migration of clear cell renal cell carcinoma by downregulating the expression of CDC25BSemantic proximity Read ↗

Bioinformatic analysis identifies potentially key differentially expressed genes in oncogenesis and progression of clear cell renal cell carcinomaSemantic proximity Read ↗

Higher expression of cell division cycle-associated protein 5 predicts poorer survival outcomes in hepatocellular carcinoma.Semantic proximity Read ↗

The tumor promoter role and molecular mechanism of C8orf76/CALB2 axis in clear cell renal cell carcinomaSemantic proximity Read ↗

Characterization of a G2M checkpoint-related gene model and subtypes associated with immunotherapy response for clear cell renal cell carcinomaSemantic proximity Read ↗

Cell Division Cycle-Associated Protein 8 in Pan-Cancer: A Comprehensive Prognostic and Immune Infiltration InvestigationSemantic proximity Read ↗

NDC80 status pinpoints mitotic kinase inhibitors as emerging therapeutic options in clear cell renal cell carcinomaSemantic proximity Read ↗

Transcription Factors BARX1 and DLX4 Contribute to Progression of Clear Cell Renal Cell Carcinoma via Promoting Proliferation and Epithelial–Mesenchymal TransitionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.