Article

G6PD upregulates Cyclin E1 and MMP9 to promote clear cell renal cell carcinoma progression

2020-12-09

Abstract excerpt

<h4>Background: </h4> Clear cell renal cell carcinoma (ccRCC) is a cell metabolic disease with high metastasis rate and poor prognosis. Our previous studies demonstrate that glucose-6-phosphate dehydrogenase (G6PD), the first and rate-limiting enzyme of the pentose phosphate pathway, is highly expressed in ccRCC and predicts poor outcomes of ccRCC patients. The aims of this study were to confirm the oncogenic role...

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Literature Corpus work: 06b103bf-389c-5560-9d8e-32acd58c7200
DOI: 10.21203/rs.3.rs-110205/v1

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