Article
Polymorphism in the interleukin 1 receptor antagonist gene in women with preeclampsia.
Journal of reproductive immunology - 1 Oct 2003
Faisel Fareeza, Romppanen Eeva-Liisa, Hiltunen Mikko, Helisalmi Seppo, Punnonen Kari, Salonen Jukka, Heinonen Seppo
Abstract excerpt
We have determined whether genetic variability in the gene encoding interleukin 1 receptor antagonist (IL1Ra) contributes to individual differences in susceptibility to the development of preeclampsia. The study involved 133 preeclamptic and 112 healthy control pregnant women who were genotyped for the variable copy number of 86-bp tandem repeats in intron 2 of the IL1Ra gene. Chi-square analysis was used to...
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