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Article

RB1 gene mutations are a distinct predictive factor in Merkel cell carcinoma.

Pathology international - 1 May 2021

Muto Yusuke, Ryo Eijitsu, Namikawa Kenjiro, Takahashi Akira, Ogata Dai, Fujimura Taku, Yatabe Yasushi, Aiba Setsuya, Yamazaki Naoya, Mori Taisuke

Abstract excerpt

Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine carcinoma that tends to show local recurrence and metastasis. Typically, MCC is polyomavirus (MCPyV)-associated and cytokeratin 20 (CK20) positive. However, little is known about this tumor and its origins. Here, we aimed to determine the developmental origins of MCC and to identify prognostic clinicopathologic factors. Initial examinations revealed...

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Share to Carcinoma, Merkel Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33751708
DOI: 10.1111/pin.13090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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