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Article

Meta-analysis and systematic review of the effect of the donor and recipient CYP3A5 6986A>G genotype on tacrolimus dose requirements in liver transplantation.

Pharmacogenetics and genomics - 1 Oct 2013

Rojas Luis E, Herrero María J, Bosó Virginia, García-Eliz María, Poveda José L, Librero Julian, Aliño Salvador F

Abstract excerpt

OBJECTIVE: A meta-analysis was carried out of published studies on the effect of the CYP3A5 6986A>G polymorphism in liver donors and transplant recipients on tacrolimus pharmacokinetics. METHODS: Cohort studies that evaluated the relationship between the CYP3A5 polymorphism in liver donors and transplant recipients and tacrolimus, trough blood concentration normalized for the daily dose (C) per kilogram body...

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Identifiers

PMID: 23873120
DOI: 10.1097/FPC.0b013e3283642fb3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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