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Article

In vitro susceptibility to benznidazole, nifurtimox and posaconazole of Trypanosoma cruzi isolates from Paraguay

Biomedica : revista del Instituto Nacional de Salud - 2 Dec 2020

Acosta Nidia, Yaluff Gloria, López Elsa, Bobadilla Christopher, Ramírez Analía, Fernández Ivana, Escobar Patricia

Abstract excerpt

Introduction: Trypanosoma cruzi, the causative agent of Chagas disease, shows substantial phenotypic and genotypic heterogeneity, which can influence the epidemiological and clinical variations of the disease and the sensitivity to the drugs used in the treatment. Objective: To assess the in vitro susceptibility to benznidazole, nifurtimox, and posaconazole of 40 cloned strains of T. cruzi isolated in Paraguay...

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PMID: 33275352
DOI: 10.7705/biomedica.5187
PMCID: PMC7808768

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