Article
Inside-out chicken enteroids with leukocyte component as a model to study host-pathogen interactions.
Communications biology - 19 Mar 2021
Nash Tessa J, Morris Katrina M, Mabbott Neil A, Vervelde Lonneke
Abstract excerpt
Mammalian three-dimensional (3D) enteroids mirror in vivo intestinal organisation and are powerful tools to investigate intestinal cell biology and host-pathogen interactions. We have developed complex multilobulated 3D chicken enteroids from intestinal embryonic villi and adult crypts. These avian enteroids develop optimally in suspension without the structural support required to produce mammalian enteroids,...
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