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Characterization of the zebrafish <i> gabra1 <sup>sa43718/sa43718</sup> </i> germline loss of function allele confirms a function for Gabra1 in motility and nervous system development

2023-01-27

Abstract excerpt

<h4>Summary</h4> Mutation of the GABRA1 gene is associated with neurodevelopmental defects and epilepsy. GABRA1 encodes for the α1 subunit of the gamma-aminobutyric acid type A receptor (GABA A R), which regulates the fast inhibitory impulses of the nervous system. Multiple model systems have previously been developed to understand the function of GABRA1 during development, but these models have produced comp...

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Literature Corpus work
0d55bae6-9be5-58c9-b8cf-a103058cea5e
DOI
10.1101/2023.01.27.525860
Open publication

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Characterization of the zebrafish <i> gabra1 <sup>sa43718/sa43718</sup> </i> germline loss of function allele confirms a function for Gabra1 in motility and nervous system developmentDOI 10.1101/2023.01.27.525860
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