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Article

A Cas12a-based gene editing system for Phytophthora infestans reveals monoallelic expression of an elicitor.

Molecular plant pathology - 1 Jun 2021

Ah-Fong Audrey M V, Boyd Amy M, Matson Michael E H, Judelson Howard S

Abstract excerpt

Phytophthora infestans is a destructive pathogen of potato and a model for investigations of oomycete biology. The successful application of a CRISPR gene editing system to P. infestans is so far unreported. We discovered that it is difficult to express CRISPR/Cas9 but not a catalytically inactive form in transformants, suggesting that the active nuclease is toxic. We were able to achieve editing with...

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Identifiers

PMID: 33724663
DOI: 10.1111/mpp.13051
PMCID: PMC8126191

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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