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Article

SWI/SNF chromatin remodeling complex alterations in meningioma.

Journal of cancer research and clinical oncology - 1 Nov 2021

Gill Corey M, Loewenstern Joshua, Rutland John W, Arib Hanane, Pain Margaret, Umphlett Melissa, Kinoshita Yayoi, McBride Russell B, Bederson Joshua, Donovan Michael, Sebra Robert, Fowkes Mary, Shrivastava Raj K

Abstract excerpt

PURPOSE: While SWI/SNF chromatin remodeling complex alterations occur in approximately 20% of cancer, the frequency and potential impact on clinical outcomes in meningiomas remains to be comprehensively elucidated. METHODS: A large series of 255 meningiomas from a single institution that was enriched for high grade and recurrent lesions was identified. We performed next-generation targeted sequencing of known...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33715086
DOI: 10.1007/s00432-021-03586-7

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