Article
Next generation sequencing identifies novel potential actionable mutations for grade I meningioma treatment.
Histology and histopathology - 1 Jul 2020
Pepe Francesco, Pisapia Pasquale, Del Basso de Caro Maria Laura, Conticelli Floriana, Malapelle Umberto, Troncone Giancarlo, Martinez Juan Carlos
Abstract excerpt
Meningiomas are common brain tumors that arise from the meningeal membranes that envelope the brain and spinal cord. The World Health Organization classifies these tumors into three histopathological grades. Because of tumor recurrence, treating meningiomas may be challenging even in well-differentiated grade I (GI) neoplasms. Indeed, around 5% of completely resected GI meningiomas relapse within 5 years....
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