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Autophagy, an accomplice or antagonist of drug resistance in HCC?

12 Mar 2021

Abstract excerpt

Hepatocellular carcinoma (HCC) is a highly lethal malignancy characterized by poor prognosis and a low 5-year survival rate. Drug treatment is proving to be effective in anti-HCC. However, only a small number of HCC patients exhibit sensitive responses, and drug resistance occurs frequently in advanced patients. Autophagy, an evolutionary process responsible for the degradation of cellular substances, is closely...

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PMID: 33712559
DOI: 10.1038/s41419-021-03553-7

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