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Article

Autophagy and liver cancer

15 May 2018

Abstract excerpt

Autophagy is a key biological phenomenon conserved from yeast to mammals. Under basal conditions, activation of autophagy leads to the protein degradation as well as damaged organelles for maintaining cellular homeostasis. Deregulation of autophagy has been identified as a key mechanism contributing to the pathogenesis and progression of several liver diseases, including hepatocellular carcinoma (HCC), one of the...

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PMID: 29755011
DOI: 10.5152/tjg.2018.150318

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