Article
Relationships between C-reactive protein concentration and genotype in healthy volunteers.
Clinical chemistry and laboratory medicine - 1 Jan 2009
Jones Jennifer, Chen Li-Sheng, Baudhuin Linnea, Peterson Sandra, Harmsen W Scott, Zinsmeister Alan R, McConnell Joseph, Sandborn William J
Abstract excerpt
BACKGROUND: Polymorphisms of the gene for C-reactive protein (CRP) alter baseline serum CRP concentrations. The impact of polymorphisms of the CRP gene (genotype) on the normal range for CRP concentrations (phenotype) has not been determined. This study evaluated the median serum CRP concentrations in normal subjects stratified for CRP genotype, after adjustment for relevant covariates as well as polymorphisms in...
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