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Article

Association of Genetically Predicted Serum Estradiol With Risk of Thromboembolism in Men: A Mendelian Randomization Study.

The Journal of clinical endocrinology and metabolism - 13 Jul 2021

Nethander Maria, Quester Johan, Vandenput Liesbeth, Ohlsson Claes

Abstract excerpt

CONTEXT: An association was recently reported between genetic markers related to high testosterone and increased risk of thromboembolism in men, but a possible causal role of estradiol for risk of thromboembolism in men remains unknown. OBJECTIVE: This work aimed to determine whether endogenous estradiol has a causal role in thromboembolism in men. METHODS: A 2-sample mendelian randomization study using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33705547
DOI: 10.1210/clinem/dgab164
PMCID: PMC8277207

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