Evasion of Immunological Memory by S. aureus Infection: Implications for Vaccine Design

Abstract excerpt

RecurrentS. aureusinfections are common, suggesting that natural immune responses are not protective. All candidate vaccines tested thus far have failed to protect againstS. aureusinfections, highlighting an urgent need to better understand the mechanisms by which the bacterium interacts with the host immune system to evade or prevent protective immunity. Although there is evidence in murine models that both...

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