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Article

Lost in deletion: The enigmatic ORF8 protein of SARS-CoV-2.

Biochemical and biophysical research communications - 29 Jan 2021

Zinzula Luca

Abstract excerpt

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome contains nine open reading frames (ORFs) that encode for accessory proteins which, although dispensable for viral replication, are important for the modulation of the host infected cell metabolism and innate immunity evasion. Among those, the ORF8 gene encodes for the homonymous multifunctional, highly immunogenic, immunoglobulin-like protein...

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Identifiers

PMID: 33685621
DOI: 10.1016/j.bbrc.2020.10.045
PMCID: PMC7577707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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