Article
Revealing the BRD4-NOTCH3 fusion: A novel hill in the cancer landscape.
Lung cancer (Amsterdam, Netherlands) - 1 Apr 2021
Costa Fabiano de Almeida, Amano Mariane Tami, Asprino Paula Fontes, Pavlick Dean C, Masotti Cibele, Testagrossa Leonardo, de Castro Gilberto
Abstract excerpt
OBJECTIVES: Gene fusions are becoming more evident in cancer scenario for either being the driver alterations, or for the great therapeutic target potential in many cases. Our aim was to characterize the BRD4-NOTCH3 fusion correlating with clinical features, and to determine the frequency of this fusion in the oncological population. MATERIAL AND METHODS: One patient diagnosed with lung adenocarcinoma at Hospital...
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