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Extracellular matrix and heart development

25 May 2011

Abstract excerpt

The extracellular matrix (ECM) of the developing heart contains numerous molecules that form a dynamic environment that plays an active and crucial role in the regulation of cellular events. ECM molecules found in the heart include hyaluronan, fibronectin, fibrillin, proteoglycans, and collagens. Tight regulation of the spatiotemporal expression, and the proteolytic processing of ECM components by proteases...

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PMID: 21618406
DOI: 10.1002/bdra.20810

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