Article
Severe Genotype, Pancreatic Insufficiency and Low Dose of Pancreatic Enzymes Associate with Abnormal Serum Sterol Profile in Cystic Fibrosis.
Biomolecules - 19 Feb 2021
Drzymała-Czyż Sławomira, Krzyżanowska-Jankowska Patrycja, Dziedzic Krzysztof, Lisowska Aleksandra, Kurek Szymon, Goździk-Spychalska Joanna, Kononets Victoria, Woźniak Dagmara, Mądry Edyta, Walkowiak Jarosław
Abstract excerpt
BACKGROUND: Several factors could lead to lipid disturbances observed in cystic fibrosis (CF). This study aimed to assess sterol homeostasis in CF and define potential exogenous and endogenous determinants of lipid dysregulation. METHODS: The study involved 55 CF patients and 45 healthy subjects (HS). Sterol concentrations (μg/dL) were measured by gas chromatography/mass spectrometry. CF was characterised by lung...
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