Article
The pancreas in cystic fibrosis.
Paediatric respiratory reviews - 1 Mar 2002
Taylor C J, Aswani N
Abstract excerpt
The pancreas secretes a bicarbonate-rich fluid containing digestive enzymes via the ampulla of Vater into the duodenum. Defective secretion leads to maldigestion of fat and protein with increased faecal losses. Cystic fibrosis (CF) is the major cause of pancreatic exocrine failure in childhood, whereas pancreatic insufficiency in adults is commonly associated with chronic pancreatitis and alcohol ingestion. In...
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