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Article

The Impact of Highly Effective CFTR Modulators on Growth and Nutrition Status.

Nutrients - 24 Aug 2021

Bass Rosara, Brownell Jefferson N, Stallings Virginia A

Abstract excerpt

Patients with cystic fibrosis (CF) are at increased risk of malnutrition and growth failure due to multiple factors as a result of suboptimal or absent function of the CFTR chloride channel protein. Dysfunctional CFTR contributes to increased energy expenditure, exocrine pancreatic insufficiency causing impaired dietary macronutrient digestion and absorption, intestinal dysbiosis, and impaired bile acid...

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Identifiers

PMID: 34578785
DOI: 10.3390/nu13092907
PMCID: PMC8470943

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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