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Article

The RNAi Mechanism Regulates a New Exonuclease Gene Involved in the Virulence of Mucorales.

International journal of molecular sciences - 25 Feb 2021

Pérez-Arques Carlos, Navarro-Mendoza María Isabel, Murcia Laura, Navarro Eusebio, Garre Victoriano, Nicolás Francisco Esteban

Abstract excerpt

Mucormycosis is a lethal disease caused by Mucorales, which are emerging as human causes that explain the high mortality for this disease. Consequently, the research community is searching for virulence determinants that could be repurposed as targets to develop new treatments against mucormycosis. Our work explores an RNA interference (RNAi)-based approach to find targets involved in the virulence of Mucorales....

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Share to Exonucleases
Share to Gene Expression Regulation, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33668930
DOI: 10.3390/ijms22052282
PMCID: PMC7956310

Provenance

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