Article
The RNAi machinery controls distinct responses to environmental signals in the basal fungus Mucor circinelloides.
BMC genomics - 25 Mar 2015
Nicolás Francisco E, Vila Ana, Moxon Simon, Cascales María D, Torres-Martínez Santiago, Ruiz-Vázquez Rosa M, Garre Victoriano
Abstract excerpt
BACKGROUND: RNA interference (RNAi) is a conserved mechanism of genome defence that can also have a role in the regulation of endogenous functions through endogenous small RNAs (esRNAs). In fungi, knowledge of the functions regulated by esRNAs has been hampered by lack of clear phenotypes in most mutants affected in the RNAi machinery. Mutants of Mucor circinelloides affected in RNAi genes show defects in...
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