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Article

RNAi-Based Functional Genomics Identifies New Virulence Determinants in Mucormycosis

20 Jan 2017

Abstract excerpt

Mucorales are an emerging group of human pathogens that are responsible for the lethal disease mucormycosis. Unfortunately, functional studies on the genetic factors behind the virulence of these organisms are hampered by their limited genetic tractability, since they are reluctant to classical genetic tools like transposable elements or gene mapping. Here, we describe an RNAi-based functional genomic platform...

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PMID: 28107502
DOI: 10.1371/journal.ppat.1006150

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