Article
Whole‑genome scale identification of methylation markers specific for cerebral palsy in monozygotic discordant twins.
Molecular medicine reports - 1 Dec 2017
Jiao Zhe, Jiang Zhimei, Wang Jingtao, Xu Hui, Zhang Qiang, Liu Shuang, Du Ning, Zhang Yuanyuan, Qiu Hongbin
Abstract excerpt
Cerebral palsy (CP) is a severe type of brain disease affecting movement and posture. Although CP has strong genetic and environmental components, considerable differences in the methylome between monozygotic (MZ) twins discordant for CP implicates epigenetic contributors as well. In order to determine the differences in methylation in patients with CP without interference of the interindividual genomic...
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