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Article

Rapid and simple SNP genotyping for Bordetella pertussis epidemic strain MT27 based on a multiplexed single-base extension assay.

Scientific reports - 1 Mar 2021

Kamachi Kazunari, Yao Shu-Man, Chiang Chuen-Sheue, Koide Kentaro, Otsuka Nao, Shibayama Keigo

Abstract excerpt

Multilocus variable-number tandem repeat analysis (MLVA) is widely used for genotyping of Bordetella pertussis, the causative bacteria for pertussis. However, MLVA genotyping is losing its discriminate power because prevalence of the epidemic MT27 strain (MLVA-27) is increasing worldwide. To address this, we developed a single nucleotide polymorphism (SNP) genotyping method for MT27 based on multiplexed...

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Share to Bordetella pertussis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 33649512
DOI: 10.1038/s41598-021-84409-0
PMCID: PMC7921669

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