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Article

Studying Bordetella pertussis populations by use of SNPeX, a simple high-throughput single nucleotide polymorphism typing method.

Journal of clinical microbiology - 1 Mar 2015

Zeddeman Anne, Witteveen Sandra, Bart Marieke J, van Gent Marjolein, van der Heide Han G J, Heuvelman Kees J, Schouls Leo M, Mooi Frits R

Abstract excerpt

Large outbreaks of pertussis occur despite vaccination. A first step in the analyses of outbreaks is strain typing. However, the typing of Bordetella pertussis, the causative agent of pertussis, is problematic because the available assays are insufficiently discriminatory, not unequivocal, time-consuming, and/or costly. Here, we describe a single nucleotide primer extension assay for the study of B. pertussis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25568442
DOI: 10.1128/JCM.02995-14
PMCID: PMC4390674

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