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Article

SNP-based typing: a useful tool to study Bordetella pertussis populations.

PloS one - 1 Jan 2011

van Gent Marjolein, Bart Marieke J, van der Heide Han G J, Heuvelman Kees J, Kallonen Teemu, He Qiushui, Mertsola Jussi, Advani Abdolreza, Hallander Hans O, Janssens Koen, Hermans Peter W, Mooi Frits R

Abstract excerpt

To monitor changes in Bordetella pertussis populations, mainly two typing methods are used; Pulsed-Field Gel Electrophoresis (PFGE) and Multiple-Locus Variable-Number Tandem Repeat Analysis (MLVA). In this study, a single nucleotide polymorphism (SNP) typing method, based on 87 SNPs, was developed and compared with PFGE and MLVA. The discriminatory indices of SNP typing, PFGE and MLVA were found to be 0.85, 0.95...

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Share to Bordetella pertussis
Share to Electrophoresis, Gel, Pulsed-Field

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Evolution, Molecular

Share to Phylogeny

Share to Polymorphism, Single Nucleotide

Share to Tandem Repeat Sequences

Source

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Identifiers

PMID: 21647370
DOI: 10.1371/journal.pone.0020340
PMCID: PMC3103551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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