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Mapping leprosy-associated coding variants of interleukin genes by targeted sequencing.

Clinical genetics - 1 Jun 2021

Zhang Deng-Feng, Li Hui-Long, Zheng Quanzhen, Bi Rui, Xu Min, Wang Dong, Zhu Guo-Ping, Li Yu-Ye, Yao Yong-Gang

Abstract excerpt

Previous genotyping-based assays have identified non-coding variants of several interleukins (ILs) being associated with genetic susceptibility to leprosy. However, understanding of the involvement of coding variants within all IL family genes in leprosy was still limited. To obtain the full mutation spectrum of all ILs in leprosy, we performed a targeted deep sequencing of coding regions of 58 ILs genes in 798...

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PMID: 33646620
DOI: 10.1111/cge.13945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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