Article
The Continuous Surveillance of InSTI Resistance Could be an Important Public Health Tool in the Fight Against HIV Infection.
Current HIV research - 1 Jan 2021
Visalli Giuseppa, Facciolà Alessio, Costanzo Maria Giovanna, Di Pietro Angela
Abstract excerpt
AIMS: To evaluate the frequency of the InSTIs mutations in a large cohort of HIV-infected people. BACKGROUND: The Highly Active Anti-Retroviral Therapy (HAART) allows turning HIV infection from a fatal disease to chronic infection, and Integrase Strand Transfer Inhibitors (InSTIs) represent the cornerstone of this treatment. However, the spread of HIV-1 drug resistance mutations represents an emerging threat to...
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