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Article

Surveillance of HIV-1 transmitted integrase strand transfer inhibitor resistance in the UK.

The Journal of antimicrobial chemotherapy - 1 Nov 2020

Mbisa Jean L, Ledesma Juan, Kirwan Peter, Bibby David F, Manso Carmen, Skingsley Andrew, Murphy Gary, Brown Alison, Dunn David T, Delpech Valerie, Geretti Anna Maria

Abstract excerpt

BACKGROUND: HIV treatment guidelines have traditionally recommended that all HIV-positive individuals are tested for evidence of drug resistance prior to starting ART. Testing for resistance to reverse transcriptase inhibitors and PIs is well established in routine care. However, testing for integrase strand transfer inhibitor (InSTI) resistance is less consistent. OBJECTIVES: To inform treatment guidelines by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32728703
DOI: 10.1093/jac/dkaa309
PMCID: PMC7566560

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