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Successful Prevention of Transmission of Integrase Resistance in the Swiss HIV Cohort Study

29 Apr 2016

Abstract excerpt

The prevalence of integrase strand transfer inhibitor (INSTI)-transmitted drug resistance (TDR) may increase with the increasing use of INSTIs. We analyzed the prevalence of INSTI TDR in the Swiss HIV Cohort Study (2008-2014). In 1 of 1316 drug-naive samples (0.1%), a major INSTI TDR mutation was detected. Prevalence was stable, although INSTIs were increasingly used. We showed that this is in contrast to the...

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PMID: 27130429
DOI: 10.1093/infdis/jiw165

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