Article
Prevalence of Integrase Strand Transfer Inhibitors (INSTI) Resistance Mutations in Taiwan.
Scientific reports - 25 Oct 2016
Chang Sui-Yuan, Lin Pi-Han, Cheng Chien-Lin, Chen Mao-Yuan, Sun Hsin-Yun, Hsieh Szu-Min, Sheng Wang-Huei, Su Yi-Ching, Su Li-Hsin, Chang Shu-Fang, Liu Wen-Chun, Hung Chien-Ching, Chang Shan-Chwen
Abstract excerpt
Antiretroviral therapy containing an integrase strand transfer inhibitor (INSTI) plus two NRTIs has become the recommended treatment for antiretroviral-naive HIV-1-infected patients in the updated guidelines. We aimed to determine the prevalence of INSTI-related mutations in Taiwan. Genotypic resistance assays were performed on plasma from ARV-naïve patients (N = 948), ARV-experienced but INSTI-naive patients...
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