Article
HIV-1 integrase drug-resistance mutations in Iranian treatment-experienced HIV-1-infected patients.
Archives of virology - 1 Jan 2020
Marjani Arezoo, Bokharaei-Salim Farah, Jahanbakhshi Fatemeh, Monavari Seyed Hamidreza, Esghaei Maryam, Kalantari Saeed, Kiani Seyed Jalal, Ataei-Pirkooh Angila, Fakhim Atousa, Keyvani Hossein
Abstract excerpt
The latest class of antiretrovirals (ARVs), including integrase strand transfer inhibitors (INSTIs), has been demonstrated to be effective for antiretroviral therapy (ART). Despite all the distinguishing characteristics of these drugs, including a high genetic barrier to resistance and lower toxicity than other ARVs, unfortunately, INSTI drug resistance mutations (DRMs) have occasionally been observed. The aim of...
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