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Article

Rs884225 polymorphism is associated with primary hypertension by compromising interaction between epithelial growth factor receptor (EGFR) and miR-214.

Journal of cellular and molecular medicine - 1 Apr 2021

Luo Fang, Wu Yitian, Ding Qunfang, Yuan Yiming, Jia Weiguo

Abstract excerpt

Genetic variations in the 3'UTR of mRNAs as well as sequences of microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) can affect gene expression by interfering with the binding between them. In this study, we investigated the role of the following polymorphisms in the risk of hypertension: the 774T > C (rs17337023) polymorphism located in the EGFR 3' untranslated region (3'UTR), the rs884225 polymorphism located...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to 3' Untranslated Regions
Share to Binding Sites
Share to ErbB Receptors
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Identifiers

PMID: 33635564
DOI: 10.1111/jcmm.15976
PMCID: PMC8051725

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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