Article
()-Epigallocatechin-3-Gallate Inhibits EBV Lytic Replication via Targeting LMP1-Mediated MAPK Signal Axes.
Oncology research - 7 Sept 2021
Li Hongde, Li Yueshuo, Hu Jianmin, Liu Sufang, Luo Xiangjian, Tang Min, Bode Ann M, Dong Zigang, Liu Xinqi, Liao Weihua, Cao Ya
Abstract excerpt
EpsteinBarr virus (EBV)-encoded latent membrane protein 1 (LMP1) plays an important oncogenic role in the viral latent infection. Recently, increasing evidence indicates that the high expression of LMP1 during EBV lytic cycle is related to the viral lytic replication. However, the mechanism by which LMP1 regulates EBV lytic replication remains unclear. ()-Epigallocatechin-3-gallate (EGCG) prevents carcinogenesis...
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