Article
Mycobacterium abscessus Strain Morphotype Determines Phage Susceptibility, the Repertoire of Therapeutically Useful Phages, and Phage Resistance.
mBio - 30 Mar 2021
Dedrick Rebekah M, Smith Bailey E, Garlena Rebecca A, Russell Daniel A, Aull Haley G, Mahalingam Vaishnavi, Divens Ashley M, Guerrero-Bustamante Carlos A, Zack Kira M, Abad Lawrence, Gauthier Christian H, Jacobs-Sera Deborah, Hatfull Graham F
Abstract excerpt
Mycobacterium abscessus is an opportunistic pathogen whose treatment is confounded by widespread multidrug resistance. The therapeutic use of bacteriophages against Mycobacterium abscessus infections offers a potential alternative approach, although the spectrum of phage susceptibilities among M. abscessus isolates is not known. We determined the phage infection profiles of 82 M. abscessus recent clinical...
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