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Anti-NLRP3 Inflammasome Natural Compounds: An Update

1 Feb 2021

Abstract excerpt

The nucleotide-binding domain and leucine-rich repeat related (NLR) family, pyrin domain containing 3 (NLRP3) inflammasome is a multimeric protein complex that recognizes various danger or stress signals from pathogens, the host, and the environment, leading to activation of caspase-1 and inducing inflammatory responses. This pro-inflammatory protein complex plays critical roles in pathogenesis of a wide range of...

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PMID: 33535473
DOI: 10.3390/biomedicines9020136

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