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Article

Response assessment during chemoradiation using a hypercellular/hyperperfused imaging phenotype predicts survival in patients with newly diagnosed glioblastoma.

Neuro-oncology - 1 Sept 2021

Kim Michelle M, Aryal Madhava P, Sun Yilun, Parmar Hemant A, Li Pin, Schipper Matthew, Wahl Daniel R, Lawrence Theodore S, Cao Yue

Abstract excerpt

BACKGROUND: Adversely prognostic hypercellular and hyperperfused regions of glioblastoma (GBM) predict progression-free survival, and are a novel target for dose-intensified chemoradiation (chemoRT) recently implemented in a phase II clinical trial. As a secondary aim, we hypothesized that dose-intensified chemoRT would induce greater mid-treatment response of hypercellular/hyperperfused tumor regions vs standard...

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Identifiers

PMID: 33599755
DOI: 10.1093/neuonc/noab038
PMCID: PMC8408852

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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