Article

Low Perfusion Compartments in Glioblastoma Quantified by Advanced Magnetic Resonance Imaging and Correlated with Patient Survival

2017-08-25

Abstract excerpt

<h4>Background</h4> Glioblastoma exhibits profound intratumoral heterogeneity in blood perfusion, which may cause inconsistent therapy response. Particularly, low perfusion may create hypoxic microenvironment and induce resistant clones. Thus, developing validated imaging approaches that define low perfusion compartments is crucial for clinical management. <h4>Methods</h4> A total of 112 newly-diagnosed supraten...

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Literature Corpus work: 583b30a4-bb24-58e2-87d2-41e95918fee9
DOI: 10.1101/180521

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