Article
Reduced viscosity mutants of Trichoderma reesei with improved industrial fermentation characteristics.
Journal of industrial microbiology & biotechnology - 30 Apr 2021
Bodie Elizabeth, Virag Aleksandra, Pratt Robert J, Leiva Nicholas, Ward Michael, Dodge Tim
Abstract excerpt
Morphological mutants of Trichoderma reesei were isolated following chemical or insertional mutagenesis. The mutant strains were shown to have reduced viscosity under industrially relevant fermentation conditions and to have maintained high specific productivity of secreted protein. This allowed higher biomass concentration to be maintained during the production phase and, consequently, increased volumetric...
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