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Article

Random and direct mutagenesis to enhance protein secretion in Ashbya gossypii.

Bioengineered - 1 Jan 2000

Ribeiro Orquídea, Magalhães Frederico, Aguiar Tatiana Q, Wiebe Marilyn G, Penttilä Merja, Domingues Lucília

Abstract excerpt

To improve the general secretion ability of the biotechnologically relevant fungus Ashbya gossypii, random mutagenesis with ethyl methane sulfonate (EMS) was performed. The selection and screening strategy followed revealed mutants with improved secretion of heterologous Trichoderma reesei endogl...

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Source

Open in PubMed Open full text

Identifiers

PMID: 23644277
DOI: 10.4161/bioe.24653
PMCID: PMC3813532

Genes

GAS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23644277-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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