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Article

Improved analysis of long STR amplicons from degraded single source and mixed DNA.

International journal of legal medicine - 1 Jul 2013

Westen Antoinette A, van der Gaag Kristiaan J, de Knijff Peter, Sijen Titia

Abstract excerpt

DNA profiles from degraded samples often suffer from information loss at the longer short tandem repeat (STR) loci. Sensitising the reactions, either by performing additional PCR cycles or increasing the capillary electrophoresis injection settings, carries the risk of over-amplifying or overloading the shorter fragments. We explored whether profiling of degraded DNA can be improved by preferential capturing of...

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PMID: 23306520
DOI: 10.1007/s00414-012-0816-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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